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BP504TSemester 52 creditsTheory

Pharmaceutical Dosage Form II

Complete unit-wise syllabus for BP504T as per the PCI B.Pharm NEP 2020 curriculum (Semester 5 — QA + Innovation + Drug Delivery).

All Sem 5 Subjects
URL:https://pharmacode.in/syllabus/semester-5/bp504t-pharmaceutical-dosage-form-ii/

Unit-wise Syllabus

5 Units
1
Controlled Release Drug Delivery Systems6 Hours
  • Rationale for controlled release; advantages and limitations; classification: sustained release, extended release, pulsatile release, delayed release
  • Diffusion-controlled systems: reservoir and matrix types; Higuchi equation; erosion-controlled and osmotic systems (OROS)
  • Biopharmaceutical Classification System (BCS): Class I-IV; biopharmaceutics and its impact on CDDS design; IVIVC
2
Transdermal Drug Delivery Systems6 Hours
  • Skin as a barrier: anatomy, permeation routes; factors affecting skin penetration (physicochemical properties, skin condition)
  • Transdermal patches: types (membrane-controlled, matrix, drug-in-adhesive, microreservoir); excipients; permeation enhancers; manufacturing
  • Marketed transdermal products: nitroglycerin, scopolamine, nicotine, fentanyl, oestradiol patches — design and clinical use
3
Ocular, Nasal and Pulmonary Drug Delivery6 Hours
  • Ocular drug delivery: anatomy and barriers; conventional (eye drops, ointments) and novel (ocular inserts, nanoparticles, contact lenses) systems; factors affecting ocular bioavailability
  • Nasal drug delivery: anatomy; drug absorption via nasal route; formulation considerations; nasal sprays, nasal gels; systemic delivery via nasal route
  • Pulmonary drug delivery: anatomy; MDI, DPI, nebulisers — formulation, devices, particle size considerations; regulatory requirements
4
Targeted Drug Delivery — Nanoparticulate Systems6 Hours
  • Targeted drug delivery: concept; passive (EPR effect) and active targeting (receptor-mediated); targeted cancer therapy
  • Liposomes: structure, preparation (thin film hydration, extrusion), characterization (size, zeta potential, entrapment efficiency); Doxil, AmBisome — marketed products
  • Polymeric nanoparticles, solid lipid nanoparticles (SLN), nanostructured lipid carriers (NLC) — preparation, characterization, applications
5
Novel Drug Delivery Concepts6 Hours
  • Dendrimers: structure, types (PAMAM, poly-L-lysine), surface functionalisation, drug loading, pharmaceutical applications
  • Microspheres and microcapsules: preparation by emulsification-solvent evaporation, spray drying, ionotropic gelation; applications in CDDS
  • Hydrogels: classification, cross-linking mechanisms; smart hydrogels (pH-responsive, thermosensitive); applications in drug delivery and tissue engineering

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What's coming next on this page

  • Reference textbooks and recommended reading list
  • Previous year question papers (PYQ)
  • Topic-wise short notes and revision summaries
  • Suggested external resources and video tutorials

Other subjects in Semester 5

BP501TBiomedicinal ChemistryBP502TIndustrial PharmacognosyBP503TInnovation and Startup EcosystemBP505TPharmaceutical Quality AssuranceBP506TSystemic Pharmacology IIBP507PBiomedicinal Chemistry (Practical)BP508PIndustrial Pharmacognosy (Practical)BP509PPharmaceutical Dosage Form II (Practical)BP510PSystemic Pharmacology II (Practical)
BP503TBP505T